Abstract: Disruptive technology alienation refers to that technology was used to obtain illegal gains during the process of the development and application of emerging technology, which deviates from its original purpose and contradicts its mission of serving the human society. Disruptive technology alienation is based on the concept of technology supreme, which lead to technological development and application that violates laws or social ethics. It has become a threat to the digital era and an critical challenge for both national and global sustainable development goals (SDGs). However, relatively little study has systematically investigated the disruptive technology alienation. This study explores the alienation in the process of innovation and application of disruptive technology. In this paper we are trying to contribute to the current research on disruptive innovation and provides practical inspiration to cope with the challenge of technology alienation and improve the governance capacity of disruptive technologies. Drawing from responsible innovation theory and combing with interdisciplinary research perspectives, this dynamic and a process of rapid evolution and cyclical strengthening. Therefore, the risks and potential consequences brought about by disruptive technological alienation have many characteristics such as high degree of impact, all-roundness, durability and irreversibility. The main risk consequences of disruptive technological alienation are concentrated in the four aspects of technology civilianization, public opinion governance, social trust, and national security risks. 
In conclusion, it is necessary to implement responsible innovation mindset and people-oriented scientific and technological ethics during the process of innovation and commercialization of disruptive technologies. On the one hand, both the government, firms and individuals could work together from "technology-individual motivation-organizational management-national security-cultural values" and other multi-level and multi-dimensional approaches, to deal with the disruptive technology alienation, and accelerate progress disruptive technology governance capabilities and modernization of governance systems ensure that science and technology are responsible, so that disruptive technological innovations could continue to empower national development and people’s health and happiness.
On the other hand, China should also actively seek international cooperation, build a disruptive technology collaborative innovation and governance platform for co-governance and sharing, as well as work together with international players to respond to international public security risks, and apply the mindset of "technology for good" to contribute the overall sustainable development of human society.

Key words: disruptive technology, technology alienation, deepfake, responsible innovation, governance capacity
modernization